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SIDAMI - Sildenafil and Diastolic Dysfunction After Acute Myocardial Infarction (AMI)
In patients with Doppler echocardiographic signs of elevated LV filling pressures despite preserved LV systolic function after AMI treatment with the phosphodiesterase inhibitor sildenafil 40 mg three times daily for 9 weeks will compared with placebo 1. Improve resting LV filling and cardiac hemodynamics. 2. Improve exercise capacity. 3. Improve filling pattern and cardiac hemodynamics during exercise.
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