Design and Development of a Novel Food Supplement for Osteoporosis Based on Gut Microbiome Mechanisms

osteopenia, postmenopausal osteopenia, dietary supplement for osteopenia, calcium and vitamin d supplement, calcium, vitamin d and prebiotics supplement, calcium, vitamin d, prebiotics and flavonoids supplement, bone turnover markers, bone mineral density, volumetric bone mineral density, bone geometry, gut microbiota analysis, interventional