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Temozolomide, Vincristine, and Irinotecan in Treating Young Patients With Refractory Solid Tumors

Children's Oncology Group · 2005
ClinicalTrials.gov · Datasets · License: Public Domain · 2005
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protocol-specific
RATIONALE: Drugs used in chemotherapy, such as temozolomide, vincristine, and irinotecan, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of irinotecan when given together with temozolomide and vincristine in treating young patients with refractory solid tumors.
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