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Impact of Disclosing Coronary Artery Disease Polygenic Risk Score on Cardiovascular Health

Massachusetts General Hospital · 2025
ClinicalTrials.gov · Datasets · License: Public Domain · 2025
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atherosclerosiscoronary-artery-diseasegeneticsnapolygenic-risk-scoreprecision-medicine
The goal of this clinical trial is to evaluate whether disclosure of a polygenic risk score for coronary artery disease (CAD PRS) influences cardiovascular health and risk factor modification over one year among adults aged 30-75 years in the Mass General Brigham primary care network who are not currently taking LDL cholesterol-lowering medications.
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