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Etude (Study) Phase I Enox - UnFractionated Heparin (UFH)

Sanofi · 2007
ClinicalTrials.gov · Datasets · License: Public Domain · 2007
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thrombosis
Primary objective: * to characterize the pharmacokinetic and the pharmacodynamic profile after intravenous bolus injection of unfractionated heparin (UFH) after repeated sc 100 IU anti-Xa/kg (corresponding to 1 mg/kg) twice a day during 2.5 days (every 12±2hrs) administrations of enoxaparin in Caucasian healthy subjects. Secondary objective(s): * to compare the pharmacokinetic and the pharmacodynamic profile between 3 different timing of administration of the UFH * to assess the tolerability of the different anticoagulation protocols
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