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Pharmacokinetic, Safety, and Efficacy Effects of Oral LBH589 on Dextromethorphan in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer or Malignant Pleural Mesothelioma

Novartis Pharmaceuticals · 2007
ClinicalTrials.gov · Datasets · License: Public Domain · 2007
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carcinomalung-cancermalignantnon-small-cell-lungnon-small-cell-lung-cancernsclc
This study will investigate the effect of oral LBH589 on dextromethorphan, a CYP2D6 substrate, and to assess safety and efficacy of oral LBH589 when used with this co-medication in advanced stage NSCLC or malignant pleural mesothelioma patients
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