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Study in Asia of the Combination of TACE With Sorafenib in HCC Patients

Taipei Veterans General Hospital, Taiwan · 2009
ClinicalTrials.gov · Datasets · License: Public Domain · 2009
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hepatocellular-carcinoma
TACE possibly plays a significant role in contributing to a subgroup of surviving residual tumor tissue which is characterized by more aggressive biology. This explains the strong scientific rationale for exploring the role of anti-angiogenic therapy such as sorafenib to remedy and strengthen the therapeutic efficacy of TACE to combat liver cancers. Sorafenib plays a prominent auxiliary role by further suppressing the tumor growth and prolonging the time to recurrence and progression. Performing TACE under sorafenib administration may have synergic effect on hepatic tumoral lesions.
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