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Study to Monitor the Effects of Androgen Suppression Treatment on the Heart

Ottawa Heart Institute Research Corporation · 2008
ClinicalTrials.gov · Datasets · License: Public Domain · 2008
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coronary-artery-diseaseendothelial-dysfunctionprostate-cancer
Suppression of effects of androgens with male sex hormones, androgen suppression treatment (AST), has been known to reduce deaths and prolong life in advanced prostate cancer. There have, however, been concerns raised in previous studies that androgen suppression may be associated with increased rate of heart attacks, particularly in older men. This study looks at prostate cancer patients in The Ottawa Hospital Cancer Clinic to see if treating these patients with androgen suppression is associated with a decrease in blood flow to the heart muscles by using Positron Emission Tomography (PET) and brachial artery ultrasound.
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