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A Phase 2 Study of Tarlatamab in Patients With Small Cell Lung Cancer (SCLC)

Amgen · 2021
ClinicalTrials.gov · Datasets · License: Public Domain · 2021
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small-cell-lung-cancer
The main aim of this study is to: * evaluate safety and efficacy (per Response Evaluation Criteria in Solid Tumors version 1.1 \[RECIST 1.1\] by investigator) of 2 dose levels of tarlatamab for Part 1 only * evaluate anti-tumor activity of tarlatamab as determined by objective response rate (ORR) per RECIST 1.1 by blinded independent central review (BICR) for Part 1 and 2 * evaluate safety of reduced mandatory monitoring period in Cycle 1 at selected dose of tarlatamab for Part 3
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