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Strategy for Early Treatment of Exacerbations in COPD: Standing Prescriptions of Advair With a Written Action Plan in the Event of an Exacerbation

McGill University Health Centre/Research Institute of the McGill University Health Centre · 2008
ClinicalTrials.gov · Datasets · License: Public Domain · 2008
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chronic-obstructive-pulmonary-diseasecopd
The purpose of this pilot study is to determine whether early treatment of acute exacerbations of chronic obstructive pulmonary disease (AECOPD) with a combination therapy, Salmeterol + Fluticasone Propionate (SFP - Advair) will reduce the use of prednisone, known as the conventional treatment. Primary objective: To determine whether early treatment with combination therapy (SFP) can reduce the use of prednisone (the conventional treatment) in the event of an AECOPD. Secondary objectives: * To evaluate the feasibility of this treatment approach and to provide pilot data (needed for a larger multi-centre clinical trial; * To evaluate the feasibility and need of assessment during and after exacerbation onset, health-related quality of life and physical activity; * To evaluate the safety of this approach; this is in terms of the delay in starting prednisone and an unfavourable outcome (ER visits and/or hospitalization).
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