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Metabolic Phenotyping of Individuals Born Following Assisted Reproduction Techniques

University of Adelaide · 2010
ClinicalTrials.gov · Datasets · License: Public Domain · 2010
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diabetesmetabolic-syndromena
This study is to compare the effects of high fat overfeeding on metabolic risk factors in children born though assisted reproduction technologies (ART) versus children conceived naturally (controls). The investigators will utilize state of the ART measures to characterize the physiological, endocrine and molecular responses to high fat overfeeding. The investigators hypothesize that children conceived following ART will have greater responses to high fat dietary challenge and that this will be associated with DNA hypermethylation of genes that are involved in lipid metabolism.
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