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Hypoxia Inducible factor1-Alpha Genetic Polymorphism of Obstructive Sleep Apnea
Specific Aim 1. To identify specific SNPs of HIF-1 gene related to cardiovascular disease in OSA patients (CVD-OSA) 2. To assay the functional activity of high risk SNPs of HIF-1 on the transcription of VEGF gene 3. To confirm that the serum level of VEGF in CVD-OSA patients with high risk SNPs of HIF-1 are higher than CVD-OSA patients without
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