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Arterial Hypertension Related to PARP Inhibitors (ArteRIB)

University Hospital, Caen · 2021
ClinicalTrials.gov · Datasets · License: Public Domain · 2021
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cancer
Although PARP inhibitors (PARPi) have proved effective in treating many cancers, few patients receiving PARPi may experience rare but serious (or not) adverse events such as hypertension whose data are scarce. The objective was to investigate reports of hypertension related to PARPi, including olaparib, rucaparib, niraparib, talazoparib, veliparib, pamiparib, and fluzoparib using the World Health Organization's (WHO) pharmacovigilance database: VigiBase.
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