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Safety and Immunogenicity Study of a Candidate Tuberculosis Vaccine in Human Immunodeficiency Virus (HIV)-Positive Adults

GlaxoSmithKline · 2011
ClinicalTrials.gov · Datasets · License: Public Domain · 2011
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tuberculosis
The purpose of the study is to assess the safety and immunogenicity of a GlaxoSmithKline (GSK) Biologicals' candidate tuberculosis vaccine (692342) administered to Human Immunodeficiency Virus (HIV)-positive adults aged 18 to 59 years, living in a tuberculosis endemic region. Subjects will be followed-up for 3 years. Subjects will be enrolled in 3 cohorts: * HIV-positive adults on highly active antiretroviral therapy * HIV-positive adults not on highly active antiretroviral therapy * HIV-negative adults Each cohort will have 2 groups.
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