Intermittent Preventive Treatment in Infant in Mali

Studies have shown that Intermittent preventive treatment in infants (IPTi) with Sulfadoxine-pyrimethamine (SP)reduced the incidence of clinical malaria and anemia without modifying infants' serological response to EPI vaccines. Thus IPTi was seen as a potential public health tool of great benefit to the children of Africa and a logical addition to the Immunization Plus package. The objectives of this operational researcher were * to develop an implementation model for IPTi in the health care system in Mali * to assess its impact on the EPI vaccines and other health interventions coverage * and on molecular makers of resistance to SP