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Safety and Efficacy of Doxycycline in Patients With Non-Ischemic Cardiomyopathy

Virginia Commonwealth University · 2012
ClinicalTrials.gov · Datasets · License: Public Domain · 2012
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heart-failure
Non-ischemic cardiomyopathy and heart failure are highly influenced by the presence of systemic inflammation. Doxycycline is a FDA-approved drug to treat bacterial infections which also shows powerful anti-inflammatory effects. In this study we plan to determine the effects of Doxycycline in patients with stable heart failure and non-ischemic cardiomyopathy on peak of aerobic exercise capacity (peak V02) and ventilator efficiency measured with a cardiopulmonary test.
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