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Cyclosporine For The Treatment Of COVID-19(+)

Bryan Burt, MD · 2020
ClinicalTrials.gov · Datasets · License: Public Domain · 2020
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covid-19sars-cov-2
Phase IIa clinical trial in which 75 non-ICU hospital inpatients will be randomized 2:1 to 7 days of an oral formulation of cyclosporine, Neoral (2.5mg/kg PO BID) + standard of care (SOC) or no Neoral + SOC. The primary endpoint is disease severity based on the World Health Organization (WHO) COVID Ordinal Outcomes Scale, on day 14. Secondary endpoints include safety and changes in serum inflammatory markers.
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