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Residual Inflammation and Plaque Progression Long-term Evaluation

University of Cambridge · 2020
ClinicalTrials.gov · Datasets · License: Public Domain · 2020
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atherosclerosiscoronary-artery-diseaseinflammationmyocardial-infarction
Inflammation drives atherosclerotic plaque rupture triggering most acute coronary syndromes. Despite advances in diagnosis and management of atherosclerosis, patients with myocardial infarction (MI) remain at increased risk of recurrent events. The RIPPLE study aims to examine the relationship between residual coronary inflammation detected by 68Ga-DOTATATE PET in patients treated for MI to long-term plaque progression measured by CT coronary angiography (CTCA). The association between infarct-related myocardial 68Ga-DOTATATE PET and myocardial function and viability will also be assessed.
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