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Detection and Classification of Levels of Consciousness Using Parietal EEG-fNIRS During Anesthesia

Pontificia Universidad Catolica de Chile · 2022
ClinicalTrials.gov · Datasets · License: Public Domain · 2022
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anesthesiaconsciousnesseegelectroencephalographyendoscopyfnirsmachine-learning
The current evaluations of the levels of consciousness during anesthesia have limited precision. This can produce negative clinical consequences such as intraoperative awareness or neurological damage due to under- or over-infusion of anesthesia, respectively. The study's objective is to determine and classify biomarkers of electrical and hemodynamical brain activity associated with the levels of consciousness between wakefulness and anesthesia. For this purpose, a parietal electroencephalography (EEG) and a functional near-infrared spectroscopy (fNIRS) measurement paradigm will be used, as well as machine-learning. Volunteering patients (n = 25), who will be subject to an endoscopy procedure, will be measured during the infusion of anesthesia with propofol. EEG and fNIRS parameters will then be related to the Modified Ramsay clinical scale of consciousness.
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