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CD30 Targeted CAR-T in Treating CD30-Expressing Lymphomas

Immune Cell, Inc. · 2017
ClinicalTrials.gov · Datasets · License: Public Domain · 2017
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anaplastic-large-cell-lymphoma
CAR-T cells have been validated effective in treating CD19 positive B cell lymphoma. Other lymphomas like Hodgkin's lymphoma and anaplastic large cell lymphoma are CD30 positive. In this study, a newly CD30 targeted CART therapy ICAR30 is designed to specifically kill those CD30 expressing malignancies including Hodgkin's lymphoma and CD30+ anaplastic large cell lymphoma. The subjects will receive several doses of autologous ICAR30 T cells infusion and then the safety, treating effects and lasting period of these cells in vivo will be evaluated.
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