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The Effects of Dopamine on Reward Processing

Mclean Hospital · 2012
ClinicalTrials.gov · Datasets · License: Public Domain · 2012
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major-depressive-disorder
The purpose of this study is to evaluate the effects of a single low dose of the D2/D3 antagonist amisulpride on reward processing. More generally, this study will test the role of dopamine (a naturally occurring brain chemical) in depression. Hypotheses: Administration of a single low dose of the D2/D3 antagonist amisulpride will (1) improve performance in a behavioral task assessing learning from feedback and (2) boost activation in reward-related brain regions.
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