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Long-term Effects of Acoltremon vs. Control in Dry Eye Disease

The Eye Care Institute · 2026
ClinicalTrials.gov · Datasets · License: Public Domain · 2026
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This is a prospective, longitudinal, single-center study designed to evaluate the long-term changes in symptoms and tear production in subjects with dry eye disease. The study is randomized and investigator-masked, with subjects assigned to either the TRYPTYR (Acoltremon ophthalmic solution 0.003%) arm or the control arm (Refresh Classic Preservative-free). The study will be conducted at a single site, with subjects undergoing assessments at baseline and at months 1, 3, 6, 9, and 12.
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