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Social & Affective Cognition in Alzheimer's Disease & Associated Disorders

University Hospital, Lille · 2025
ClinicalTrials.gov · Datasets · License: Public Domain · 2025
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alzheimer-s-diseaseemotionsfrontotemporal-dementiananeuropsychologysocial-cognition
Recent studies have shown that individual neuropsychological scores of patients with Alzheimer's disease and Associated Disorders (ADAD) are only poorly correlated to their behavioral difficulties, such as disinhibition, apathy, social decision-making or vulnerability. Recently, social \& affective cognitive disorders have been highlighted as potential cause of social behavioral abnormalities. However, no previous studies have assessed the specific relationship between social \& affective cognition \& social behavior in ADAD. Our pilot study aims to explore the correlations between core and extended social \& affective cognitive processes and social behavior as observed during the neuropsychological examination, as well as to explore the common brain regions involved in those domains.
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