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Lowering InterLeukin-1 Receptor Antagonist Concentrations After TB Treatment Onset

ANRS, Emerging Infectious Diseases · 2020
ClinicalTrials.gov · Datasets · License: Public Domain · 2020
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tuberculosis
Despite marked improvements in the diagnosis of tuberculosis there are difficulties in diagnosing and monitoring treatment outcome among TB patients. The use of immunological biomarkers alone or in combination with other clinical parameters could predict early the response to TB treatment. The aim of this study is to demonstrate that the IL-1 receptor antagonist (IL-1Ra) concentrations significantly decrease within two weeks following TB treatment initiation in adults with active documented TB.
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