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Carboplatin Taxol Avastin in Ovarian Cancer (OVCA)

Massachusetts General Hospital · 2005
ClinicalTrials.gov · Datasets · License: Public Domain · 2005
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bevacizumabcancerovarianovarian-cancerpaclitaxel
Study Design: This ia a Phase II study. Subjects: Patients with chemotherapy naive epithelial ovarian cancer; or fallopian, primary peritoneal and papillary serous mullerian tumors will be recruited. Carboplatin and Taxol (paclitaxel) will be administered concurrently with bevacizumab after surgery for 6-8 cycles every 21 (q21) days. Bevacizumab will be omitted in the first cycle, immediately post-operatively. This will be followed by one year of bevacizumab q21. Outcomes: Outcomes include toxicity, response rate, and progression free survival.
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