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VALID : VAlproate Versus LIthium in Bipolar Disorders
Primary Objective : * To compare the efficacy of valproate to lithium in Bipolar I patients suffering from a manic or a mixed episode according to DSM IV TR (APA 2000) \[Diagnostic and Statistical Manual of Mental Disorders (DSM) fourth edition (IV)Text Revision (TR)\] and over a periode of 3 weeks and 12 weeks of treatment Secondary Objective : * To evaluate the clinical and biological safety of valproate compared to lithium.
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