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Enoblituzumab (MGA271) in Children With B7-H3-expressing Solid Tumors

MacroGenics · 2016
ClinicalTrials.gov · Datasets · License: Public Domain · 2016
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neuroblastomaosteosarcomapediatricrhabdomyosarcoma
This study is a Phase 1, open-label, dose escalation and cohort expansion trial designed to characterize the safety, tolerability, PK, PD, immunogenicity and preliminary antitumor activity of enoblituzumab administered IV on a weekly schedule for up to 96 doses (approximately 2 years) in children and young adults with B7-H3-expressing relapsed or refractory malignant solid tumors.
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