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Autologous Hematopoietic Stem Cell Transplantation for Allogeneic Organ Transplant Tolerance

Gary A Levy, O. Ont. MD. FRCP AGAF · 2015
ClinicalTrials.gov · Datasets · License: Public Domain · 2015
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autoimmune-disease
This open-label, proof-of-principle two center cohort study will evaluate the ability of autologous hematopoietic stem cell transplantation to induce tolerance in recipients of deceased or live donor liver transplants (ASCOTT). A maximum of 10 participants will be entered at a minimum of 3 months post liver transplant. The participants will undergo autologous hematopoietic stem cell transplants (HSCT) to "re-educate" their immune systems to accept the graft without the need for long term immunosuppression (tolerance).
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