Conceptio › Archive › ClinicalTrials.gov
ClinicalTrials.gov public full text Public Domain

Prevalence and Risk Factors of Chronic Thrombo-embolic Disease After a Pulmonary Embolism Event

Centre Hospitalier Universitaire de Nice · 2021
ClinicalTrials.gov · Datasets · License: Public Domain · 2021
Open Source ↗
Venous thromboembolic disease (VTE) is a common clinical entity whose two manifestations are deep vein thrombosis (DVT) and pulmonary embolism (PE). After an acute PE, almost half of the patients complain residual dyspnea, despite well-conducted curative anticoagulation. Some will present persistent defects on lung scan-scintigraphy, without pulmonary hypertension. This condition defines Chronic-Thrombo-Embolic Disease(CTED). The prevalence of CTED after PE is poorly known as are its risk factors. The primary objective is to determine the prevalence of CTED at 3 or 6 months, depending on the provoked or unprovoked character, after a PE. The secondary objectives are: * To determine the potential risk factors for the occurrence of CTED. * To look for an association between the persistence of DVT and the occurrence of CTED. * To look for an association between the diagnosis of CTED and PE recurrence during the 12-month follow-up. * To determine the diagnostic performance of the clinician alone compared to the lung scintigraphy (gold standard) for the diagnosis of CTED. * To compare the impact on the quality of life (QoL) with or without CTED. * To determine the correlation between impaired QoL and the degree of residual obstruction on lung scintigraphy.
Conceptio Open Archive

Analyze & explore related research in Conceptio

Connect this record directly into your research workflow or AI agent. Explore citations across open repositories, query full text, and export structured proof bundles.

This document is indexed with metadata only: full text is not available in the archive for this record. Open the official source ↗

Related documents

Record · ID 866209
Retrieved via Conceptio: every document is proof-bundled with source, license, and retrieval metadata.
Bring this data into your agent: Connect via MCP or API · 20 free credits to start · no card required
Read the Docs → · View CLI source on GitHub · Conceptio Open Knowledge Archive