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Nanozymes in Endodontics

University of Pennsylvania · 2026
ClinicalTrials.gov · Datasets · License: Public Domain · 2026
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apical-periodontitisnanotechnology
The antimicrobial efficacy and healing potential of clinically approved ferumoxytol nanozymes versus the standard 3% NaOCl irrigant will be evaluated in adults undergoing endodontic treatment. Building on prior protocols that demonstrated ferumoxytol nanozymes antimicrobial activity as a root canal irrigant, ferumoxytol solution will be applied topically, assessment of clinical and radiographical findings will determine its potential as a novel disinfection and its long-term outcome.
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