A Randomized Controlled Trial of Gabor-Based Perceptual Learning for Adult Amblyopia

This study is initiated and conducted by the Shanghai Eye Disease Prevention and Treatment Center / Shanghai Eye Hospital. Many people once believed that amblyopia (commonly known as "lazy eye") could only be treated during childhood (the critical period of visual development) and that nothing could be done once we reached adulthood. However, modern visual science research has revealed that the adult visual cortex still retains a certain degree of "neuroplasticity" (the brain's ability to reorganize, learn, and adapt). The Gabor target training used in this study-powered by RevitalVision software-is a scientifically proven visual training program. By repeatedly performing visual tasks near your perception threshold on a computer screen, this training exercises your eye-brain coordination, helping your brain process visual information much more efficiently. To help you and your family participate with peace of mind, we have compiled the following answers to frequently asked questions: Q1: How will I participate in this study? What is the difference between the two groups? To scientifically compare the training's effectiveness, this study uses a rigorous randomized controlled design. A total of 80 eligible participants will be randomly assigned by a computer program in a 1:1 ratio to one of two groups: Immediate Training Group: You will begin the 12-week home-based Gabor visual training right after randomization. Your study participation ends after your Week 12 follow-up. Delayed Training Group: During the first 12 weeks after randomization, you will simply wear your prescribed glasses and go about your daily life without active visual training. After completing your Week 12 eye evaluation, you will receive the exact same 12-week Gabor visual training for free (conducted from Week 12 to Week 24). Please be assured: No matter which group you are assigned to, every eligible participant will ultimately receive the exact same 12-week professional visual training.