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Comparison of MCO HD on Markers of Vascular Health Compared With On-Line Haemodiafiltration

Manchester University NHS Foundation Trust · 2018
ClinicalTrials.gov · Datasets · License: Public Domain · 2018
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cardiovascular-diseasesend-stage-renal-diseasehaemodialysishemodialysisinflammationnapulse-wave-velocity
The aim of this study is to evaluate haemodialysis treatment using a medium cut-off dialysis membrane (Theranova) compared with on-line haemodiafiltration treatment with respect to markers of endothelial health (plasma endothelial microvesicle levels, pro-inflammatory and pro-coagulant markers). This study will also compare the 2 treatment modalities with respect to several other outcome measures including patient-reported outcome measures, haemodynamic parameters and advanced glycation end-products.
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