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Role of the Catechol-O-methyltransferase (COMT) in the Physiological Regulation of Vigilance
In this study, pharmacologic effects of COMT inhibition during sleep deprivation in healthy subjects in dependence of their Val158Met genotype of COMT are studied. Potential effects are identified by measurement of vigilance and cognitive performance as well as EEG measurements during wake and sleep. * Trial with medicinal product
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