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The Acute Effect of 2 Different Serving Regimens of Theobromine on Physiological Effects

Unilever R&D · 2012
ClinicalTrials.gov · Datasets · License: Public Domain · 2012
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cardiovascular-diseasesheart-ratena
The main aim of this study is to determine whether there is a difference in the physiological effects of theobromine when provided via a single serving compared to multiple servings adding up to the same amount of theobromine provided on a day. This study also aims to study the pharmacokinetics of theobromine after administration once per day versus administration 4 times per day. Hypothesis: the effects on heart rate are less pronounced when a high dose of theobromine is given in 4 smaller doses.
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