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Neurocognitive Benefits of a Weight Management Program

University of Pennsylvania · 2019
ClinicalTrials.gov · Datasets · License: Public Domain · 2019
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fmrineuroimagingobesityoverweight-and-obesityweight-loss
This study will assess whether weight loss induced through diet and physical activity can change neural responses to high- and low-calorie food images. In addition, it will evaluate whether weight loss can improve neural function when performing the N-back task, a measure of working memory. Findings will address notable gaps in the literature by testing whether a scalable weight loss intervention can help protect and improve neurocognitive functioning and brain health in individuals with obesity. This study will also provide important information about the effects of weight loss on neuroplasticity in brain regions crucial for memory and cognitive functioning, which will help to inform future interventions aimed at promoting brain health.
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