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Personalized Sertraline Dosing in Patients With Depression

University of Belgrade · 2020
ClinicalTrials.gov · Datasets · License: Public Domain · 2020
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majorpharmacogeneticsprecision-medicinepsychiatrysertraline
The aims of this study are to: 1. Determine the proportion of participants who are underdosed or overdosed under recommended dosing regimen of sertraline for the depression treatment (100 mg/day) 2. Determine and quantify clinical benefits of personalized sertraline dosing regimen based on the sertraline blood level monitoring 3. Retrospectively estimate whether the information on CYP2C19 genotype is useful in prediction of sertraline blood level.
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