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Adjuvant Sintilimab Plus Lenvatinib for HCC Characterized With VETC Following Liver Resection

Wan-Guang Zhang · 2025
ClinicalTrials.gov · Datasets · License: Public Domain · 2025
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hcchepatocellular-carcinoma-hccnapd-1recurrence
Vessels that encapsulate tumor clusters (VETC) are a novel invasive metastatic factor in hepatocellular carcinoma (HCC), operating independently of the epithelial-mesenchyme transition (EMT). The presence of VETC is associated with a higher rate of postoperative recurrence in HCC patients, indicating a more aggressive biological behavior.Improving the prognosis for VETC-positive patients is a critical issue in clinical oncology.
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