VASCULUX-examination of the Pulmonary VASCUlar Barrier in Patients During LUng Transplantation

Lung transplantation is a well established method for surgical therapy for patients with end stage pulmonary disease. The investigators seek to determine to which extent the pulmonary vascular barrier gets harmed during lung transplantation and whether pulmonary edema after reperfusion can be monitored with measurement of extravascular lung water index (ELWI). Additionally the investigaors are going to evaluate the correlation between ELWI and shedding of the endothelial glycocalyx. The study is designed as a prospective observational cohort study.