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Impact of Carbetocin Administration on Heart Rate When Given as an Infusion Versus as a Bolus.

Ciusss de L'Est de l'Île de Montréal · 2018
ClinicalTrials.gov · Datasets · License: Public Domain · 2018
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Prospective, randomized and controlled study who will be conducted at Maisonneuve-Rosemont hospital with the following objectives: To determine if an infusion of carbetocin over 10 minutes will reduce hemodynamic side effects, especially the peak of heart rate, in comparison to a rapid intravenous bolus (less than 2 seconds). To determine if an infusion of carbetocin will reduce the other side effects of duratocin in comparison to a rapid intravenous bolus. Study plans to enroll 70 adult patients scheduled to undergo elective cesarean delivery under spinal anesthesia. Half of the patient will receive Carbetocin 100 mcg intravenous as a bolus (less than 2 seconds) and the other half will receive Carbetocin 100 mcg intravenous infusion over 10 minutes.
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