Studies of Avian Influenza Transmission to Humans in Egypt

The main focus of the study is: * To estimate seroprevalence of AI in poultry-exposed and non-exposed human populations. * To estimate the incidence of AI in poultry-exposed and non-exposed human populations. * To investigate risk factors associated with AI infections in occupationally-exposed poultry workers. The secondary objectives of the study: * To investigate patterns in transmission of AI to household contacts of AI clinical cases * To isolate AI viruses from acute cases * To monitor the pathogenicity and disease severity of AI viruses causing human infections