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Neurochemical Modulation Cognitive Performance and Subjective Wellbeing In Healthy Controls

Cambridge University Hospitals NHS Foundation Trust · 2009
ClinicalTrials.gov · Datasets · License: Public Domain · 2009
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cognitivecognitive-performancecreativityhealthy-volunteersmotivationnaperformancereward
This project aims to investigate the effect of modafinil on motivation, creativity, cognitive performance, and subjective wellbeing in healthy participants. The main task for this research project is to address how this novel stimulant acutely influences motivation, divergent and convergent thinking, cognitive performance and subjective wellbeing in non-sleep deprived healthy young adults.This is a randomised between-subjects parallel group design study. Based on the hypothesis that psychostimulants might enhance creativity through the increase in of dopamine and executive planning in healthy adults , we predict that healthy individuals who are in the modafinil condition will perform better in the motivation, creativity, and the cognitive performance tasks. Furthermore, based on the evidence that modafinil increases dopamine in the nucleus accumbens, putamen and the caudate, we expect specific subjective well-being and pleasure enhancement associated with modafinil use in healthy young adults.
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