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Defining a PK and PD Model for Peripheral Analgesia After IV Oxytocin

Wake Forest University Health Sciences · 2023
ClinicalTrials.gov · Datasets · License: Public Domain · 2023
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chronic-painhealthy-volunteeroxytocin
The goal of this clinical trial is to learn about oxytocin ( a naturally occurring hormone made in the brain that transmits messages) and the effects it may have on thermal heat pain after intravenous administration. The main question it aims to define is the time course of change in pain score after a 5 minute heating of the skin administered at intervals during and following infusion of intravenous oxytocin in order to create a Pharmacokinetic and a Pharmacodynamic model for oxytocin-induced analgesia. Participants will be asked to rate thermal heat temperatures before, during and after the intravenous infusion of oxytocin.
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