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Biomarker-based Trial of NPC-1 for Alzheimer's Pathology

Massachusetts General Hospital · 2026
ClinicalTrials.gov · Datasets · License: Public Domain · 2026
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alzheimer-diseasealzheimer-s-diseasedietary-supplementsintervention
This early phase, open label, single arm clinical trial will determine the intraindividual safety, tolerability and effects of NPC1 (parthenolide and ipriflavone) on blood-based biomarkers of Alzheimer's disease (AD) pathology among adults with subjective cognitive decline, mild cognitive impairment, or Alzheimer's disease and objective indicators of seeding AD pathology
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