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Dexamethasone in Cryptococcal Meningitis

National Institute of Allergy and Infectious Diseases (NIAID)
ClinicalTrials.gov · Datasets · License: Public Domain
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acquired-immunodeficiency-syndromeamphotericin-bcombinationdrug-therapyhiv-infectionsmeningitis
To evaluate the effect of corticosteroids on reducing elevated intracranial pressure in cryptococcal meningitis. To evaluate the safety of corticosteroids in patients with cryptococcal meningitis and intracranial hypertension. In AIDS patients with cryptococcal meningitis, a correlation has been found between early death and elevated intracranial pressure. Since dexamethasone has been found to reduce intracranial pressure resulting from other forms of meningitis, it may be of benefit in AIDS patients with cryptococcal meningitis.
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