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Effect of Single Doses of YF476 on Stomach Acidity Compared With Ranitidine and Placebo in Fasted and Fed States
The objectives of the study were: * To compare a single dose of YF476 at 3 dose levels, placebo and ranitidine with respect to their effects on basal- and food- stimulated gastric pH in healthy volunteers. * To assess whether there is a relationship between the pharmacokinetics of YF476 and gastric pH in healthy volunteers. * To assess the safety and tolerability of single doses of YF476 in healthy volunteers.
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