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Sevoflurane Versus Propofol for Laryngeal Mask Airway Placement in Children Undergoing Surgery

Children's Hospital and Institute of Child Health, Multan · 2025
ClinicalTrials.gov · Datasets · License: Public Domain · 2025
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The goal of this clinical trial is to compare two commonly used anesthetic medicines, sevoflurane and propofol, for inserting a laryngeal mask airway (LMA) in children undergoing minor elective surgery. A laryngeal mask airway is a device placed in the throat to help children breathe safely during anesthesia. The main questions this study aims to answer are: * Does sevoflurane produce a faster onset of anesthesia than propofol? * Is there a difference between sevoflurane and propofol in the time required to achieve jaw relaxation for LMA insertion? * Is there a difference between the two medicines in the time required for successful LMA insertion? The researchers hypothesize that children receiving sevoflurane will have a shorter induction time than those receiving propofol. A total of 170 children aged 4 to 12 years who are undergoing minor surgical procedures below the umbilicus will participate in the study. Participants will be randomly assigned to receive either intravenous propofol or inhaled sevoflurane for induction of anesthesia. During the procedure, the anesthesia team will measure the time taken to lose consciousness, the time required to achieve adequate jaw relaxation, and the time needed for successful insertion of the laryngeal mask airway. These measurements will help determine which anesthetic agent provides better conditions for LMA insertion in children.
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