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CD70-CAR-NK Cell Therapy for T Cell Lymphoma and Acute Myeloid Leukemia

Second Affiliated Hospital, Zhejiang University, School of Medicine · 2024
ClinicalTrials.gov · Datasets · License: Public Domain · 2024
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acute-myeloid-leukemia
CD70 is a promising target for immunotherapy because it is overexpressed in T-cell lymphoma (TCL) and acute myeloid leukemia (AML) tumor cells but is found in deficient levels in normal tissues and hematopoietic stem cells. This study aims to evaluate the safety and efficacy of CD70-targeted CAR-NK (CD70-CAR-NK) cells in patients with relapsed and refractory TCL and AML.
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