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Physiological, Hormonal, and DNA-based Mechanisms of Psychosocial Stress and Therapeutic Effect

University of Helsinki · 2025
ClinicalTrials.gov · Datasets · License: Public Domain · 2025
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anxietydepressionlonelinessmental-healthpsychologicalsocial-anxietysocial-isolationuniversity-students
The goal of this trial is to learn if the Groups 4 Health (G4H) intervention is effective in supporting student well-being at the University of Helsinki. It will also learn about the factors that may influence the efficacy of the intervention (such as facilitators characteristics, stress physiology and changes in gene expression). The main questions it aims to answer are: 1. Is the G4H intervention effective and cost-effective in supporting student well-being? 2. To what extent participants' physiological, hormonal, or molecular characteristics mediate the therapeutic effect of the G4H 3. To what extent participants' genotype moderates the effect of the G4H 4. To what extent facilitators' characteristics mediate or moderate the effect of the G4H Data is collected from both the intervention participants and the facilitators. The G4H facilitators will: * Facilitate the G4H intervention. * Fill in questionnaires and provide physiological and molecular measurements before, during, and after the G4H intervention. The G4H participants will: * Participate in the G4H intervention. * Fill in questionnaires and provide physiological, hormonal and molecular measurements before, during, and after the G4H intervention.
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