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The Apple Study: Two Apples a Day, Keep the Doctor Away?

Maastricht University Medical Center · 2023
ClinicalTrials.gov · Datasets · License: Public Domain · 2023
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The goal of this clinical trial is to learn about the gut microbiome in healthy postmenopausal women aged 50-64. The main questions it aims to answer are: * Investigate whether the activity of the bacterial enzyme β-glucuronidase and the abundance of β-glucuronidase-producing bacteria could be decreased by ingestion of 2 apples a day for a period of 6 weeks * Examine changes in gut microbiota composition, diversity, and functional capacity * Examine feasibility of eating 2 apples a day for a period of 6 weeks Participants will eat 2 apples a day for a period of 6 weeks. Six weeks includes the period from the start of the study and gathering of baseline characteristics/questionnaires till the finish.
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