Polymeric Microspheres vs Sculptra® in the Treatment of Moderate to Severe Nasolabial Folds

This is a single-dose, randomized, double-blind, active-controlled, split-face, multiple centers, non-inferiority study. Approximately 50 nasolabial fold subjects will be enrolled. Each enrolled subject will be randomized equally into one of the following groups: 1. Group 1: right face will be injected with PBF PLLA microsphere, and left face with Sculptra® 2. Group 2: right face will be injected with Sculptra® and left face with PBF PLLA microsphere Subjects will be administrated on Visit 1 by applying PBF PLLA microsphere on one side of face and Sculptra® on the other.